Complete Long-Term Remission of an Inflammatory Pseudotumor under Corticosteroid Therapy

Language
en
Document Type
Article
Issue Date
2013-02-25
Issue Year
2011
Authors
Pfeifer, Lukas
Agaimy, Abbas
Janka, Rolf
Boxberger, Frank
Wein, Axel
Neurath, Markus F.
Siebler, Jürgen
Editor
Abstract

Inflammatory pseudotumors (IPT) form a group of etiologically, histologically, and biologically heterogeneous tumefactive lesions that are histologically characterized by prominent inflammatory infiltrates. IPT has been described in various organs including the lungs, bladder, liver, spleen, heart, and others. It may mimic a malignant tumor clinically and radiologically. We report a case of a 26-year-old woman with an ALK1- negative IPT (7 cm in maximal diameter) mainly located in the 12th right back muscles, surrounding a fractured rib. Histologically, the tumor consisted of an inflammatory infiltrate composed predominantly of diffusely distributed lymphoplasmacytic cells and stromal fibroblasts associated with focal obliterative phlebitis. Conservative steroid treatment resulted in complete remission and the patient remained disease-free for more than 1 year later. To our knowledge this is the first report of IPT involving the skeletal back muscle and complete resolution under corticosteroid treatment.

Journal Title
Case Reports in Oncology 2011; 4: 304-310. <http://content.karger.com/ProdukteDB/produkte.asp?typ=pdf&doi=329415> © 2011 S. Karger AG, Basel
Citation
Case Reports in Oncology 2011; 4: 304-310. <http://content.karger.com/ProdukteDB/produkte.asp?typ=pdf&doi=329415> © 2011 S. Karger AG, Basel
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