Comparison of Transrectal Prostate Biopsy Results with Histology of Transurethral Resection of the Prostate in Men Undergoing High-Intensity Focused Ultrasound

dc.contributor.authorRogenhofer, Sebastian
dc.contributor.authorWalter, Bernhard
dc.contributor.authorHartmann, Arndt
dc.contributor.authorWieland, Walter Ferdinand
dc.contributor.authorMueller, S. C.
dc.contributor.authorBlana, Andreas
dc.date.accessioned2014-05-02
dc.date.available2023-10-09T23:31:20Z
dc.date.created2013
dc.date.issued2014-05-02
dc.description.abstractIntroduction: The aim of our study was to evaluate the significance of transurethral resection of the prostate (TURP) to detect prostate cancer (PCa). A comparison was performed of the TURP specimens of patients undergoing high-intensity focused ultrasound (HIFU) with the core biopsies. Materials and Methods: TURP before undergoing HIFU therapy was performed in 106 patients without neoadjuvant treatment. The resected tissue was subjected to histopathological evaluation and compared to the histological results of transrectal prostate biopsy. Results: Cancer was detected in the resected tissue of 69 patients (65%). A positive correlation of the amount of resected tissue and detection of PCa could be demonstrated in a multivariate analysis. Conclusions: With a rate of 65% PCa detected by TURP, our data provide evidence that TURP might be suitable to detect PCa in a small group of selected patients with continuously rising PSA levels and several negative biopsies. On the other hand, these data underline/reinforce the necessity to treat the whole gland using modern treatment modalities such as HIFU and cryotherapy.en
dc.format.extent283-287
dc.identifier.citationUrologia Internationalis 2013; 90: 283-287. <http://www.karger.com/Article/Pdf/346320> © 2013 S. Karger AG, Basel
dc.identifier.doihttps://doi.org/10.1159/000346320
dc.identifier.opus-id4582
dc.identifier.urihttps://open.fau.de/handle/openfau/4582
dc.identifier.urnurn:nbn:de:bvb:29-opus4-45826
dc.language.isoen
dc.rights.urihttp://www.gesetze-im-internet.de/urhg/index.html
dc.subjectHigh-intensity focused ultrasound
dc.subjectTransurethral resection of the prostate
dc.subjectBiopsy
dc.subjectProstate cancer
dc.subject.ddcDDC Classification::6 Technik, Medizin, angewandte Wissenschaften :: 61 Medizin und Gesundheit :: 610 Medizin und Gesundheit
dc.titleComparison of Transrectal Prostate Biopsy Results with Histology of Transurethral Resection of the Prostate in Men Undergoing High-Intensity Focused Ultrasounden
dc.typearticle
dcterms.publisherFriedrich-Alexander-Universität Erlangen-Nürnberg (FAU)
local.journal.titleUrologia Internationalis
local.journal.volume90
local.sendToDnbfree*
local.subject.fakultaetMedizinische Fakultät
local.subject.sammlungUniversität Erlangen-Nürnberg / Allianzlizenzen: Alle Beiträge sind mit Zustimmung der Rechteinhaber aufgrund einer DFG-geförderten Allianzlizenz frei zugänglich. / Allianzlizenzen 2013
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