The Relevance of the Bacterial Microbiome, Archaeome and Mycobiome in Pediatric Asthma and Respiratory Disorders

Language
en
Document Type
Article
Issue Date
2022-05-06
First published
2022-04-10
Issue Year
2022
Authors
Baehren, Carolin
Buedding, Eleni
Bellm, Aliyah
Schult, Frank
Pembaur, Anton
Wirth, Stefan
Ehrhardt, Anja
Paulsen, Friedrich
Postberg, Jan
Aydin, Malik
Editor
Publisher
MDPI
Abstract

Bacteria, as well as eukaryotes, principally fungi, of the upper respiratory tract play key roles in the etiopathogenesis of respiratory diseases, whereas the potential role of archaea remains poorly understood. In this review, we discuss the contribution of all three domains of cellular life to human naso- and oropharyngeal microbiomes, i.e., bacterial microbiota, eukaryotes (mostly fungi), as well as the archaeome and their relation to respiratory and atopic disorders in infancy and adolescence. With this review, we aim to summarize state-of-the-art contributions to the field published in the last decade. In particular, we intend to build bridges between basic and clinical science.

Journal Title
Cells
Volume
11
Issue
8
Citation
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