Aminoferrocene- or ferrocenylaniline-based ROS amplifiers with anticancer activity

Language
en
Document Type
Doctoral Thesis
Issue Date
2022-04-11
Issue Year
2022
Authors
Xu, Honggui
Editor
Abstract

In this thesis, the author described several aspects including Cancer and its treatment, Intracellular ROS generation and distribution, Ferrocene-based anticancer derivatives, ROS-responsive anticancer prodrugs and Aminoferrocene-based ROS amplifiers as anticancer prodrugs. After that, the author detailly explained several projects including Optimized mitochondria-targeted aminoferrocene-based prodrugs, Endoplasmic reticulum-targeted aminoferrocene-based prodrugs, Ferrocenylaniline-based ROS amplifiers as anticancer prodrugs, Stable aminoferrocene-based anticancer derivatives and Non-toxic chemodosimeters for singlet oxygen detection.

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