Antioxidant effect of aqueous extract of four plants with therapeutic potential on gynecological diseases; Semen persicae, Leonurus cardiaca, Hedyotis diffusa, and Curcuma zedoaria

dc.contributor.authorJi, Shaojian
dc.contributor.authorFattahi, Amir
dc.contributor.authorRaffel, Nathalie
dc.contributor.authorHoffmann, Inge
dc.contributor.authorBeckmann, Matthias W.
dc.contributor.authorDittrich, Ralf
dc.contributor.authorSchrauder, Michael
dc.date.accessioned2018-01-25
dc.date.available2018-01-23
dc.date.created2017
dc.date.issued2018-01-25
dc.description.abstractBackground Little information is available concerning antioxidant effects of plant teas (water boiled) which are used more commonly in traditional Chinese medicine than other extracts. Thus, we addressed this issue by evaluating the ability of teas from four different plants with therapeutic potential on gynecological diseases. Methods The aqueous extracts of Semen persicae, Leonurus cardiaca, Hedyotis diffusa, and Curcuma zedoaria rhizome were prepared and then their effects on copper-induced low-density lipoprotein cholesterol (LDL-C) oxidation were evaluated by spectrophotometric method. Density gradient ultracentrifugation method was recruited to isolate LDL-C from healthy individuals. Results Our results showed that adding 10, 20, and 30 µl S. persicae could increase the lag phase duration of LDL-C oxidation compared with control reaction 12, 21, and 33%, respectively. The most effective delay (87%) was observed when 30 µl H. diffusa was added to the reaction. In cases of L. cardiaca and C. zedoaria, we found no significant influence on the lag phase duration (p > 0.05). Moreover, our findings about starting point of the decomposition phase were almost in parallel with the lag phase results, as 30 µl of S. persicae or H. diffusa teas could significantly increase the initiation time of decomposition (p < 0.05). Conclusions In conclusion our results showed that both S. persicae and H. diffusa teas and not L. cardiaca and C. zedoaria could have medicinal therapeutic effects partly through direct oxidation prevention.en
dc.identifier.citationEuropean Journal of Medical Research 22 (2017). <https://eurjmedres.biomedcentral.com/articles/10.1186/s40001-017-0293-6>
dc.identifier.doihttps://doi.org/10.1186/s40001-017-0293-6
dc.identifier.opus-id9331
dc.identifier.urihttps://open.fau.de/handle/openfau/9331
dc.identifier.urnurn:nbn:de:bvb:29-opus4-93319
dc.language.isoen
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/deed.de
dc.subjectAntioxidants
dc.subjectCurcuma zedoaria
dc.subjectHerbal medicine
dc.subjectHedyotis diffusa
dc.subjectLeonurus cardiac
dc.subjectSemen persicae
dc.subject.ddcDDC Classification::6 Technik, Medizin, angewandte Wissenschaften :: 61 Medizin und Gesundheit :: 610 Medizin und Gesundheit
dc.titleAntioxidant effect of aqueous extract of four plants with therapeutic potential on gynecological diseases; Semen persicae, Leonurus cardiaca, Hedyotis diffusa, and Curcuma zedoariaen
dc.typearticle
dcterms.publisherFriedrich-Alexander-Universität Erlangen-Nürnberg (FAU)
local.journal.titleEuropean Journal of Medical Research
local.journal.volume22
local.sendToDnbfree*
local.subject.fakultaetMedizinische Fakultät
local.subject.gnd-
local.subject.sammlungUniversität Erlangen-Nürnberg / Von der FAU geförderte Open Access Artikel / Von der FAU geförderte Open Access Artikel 2017
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