Multidisciplinary Late Effects Clinics for Childhood Cancer Survivors in Germany - a Two-Center Study

Language
en
Document Type
Article
Issue Date
2019-09-10
First published
2018-06-15
Issue Year
2018
Authors
Gebauer, Judith
Rieken, Sarah
Schuster, Sonja
Hahn, Birgit
Gebauer, Niklas
Meidenbauer, Norbert
Brabant, Georg
Metzler, Markus
Langer, Thorsten
Editor
Publisher
S. Karger AG
Abstract

Background: Childhood cancer survivors are at risk for therapy-related sequelae and, therefore, require long-term follow-up. At 2 university hospitals in Germany collaborative multidisciplinary late effects clinics were installed to provide specialized care and to evaluate the current health status of these patients in a clinical setting. Patients andMethods: Every patient who visited the late effects clinics at the university hospital in Lübeck and Erlangen over a period of 3 years and met the inclusion criteria was included in the study. Patients' characteristics as well as cancer diagnosis, treatment related factors and the prevalence of chronic health conditions were assessed. Results: 220 patients attended the late effects clinics during the observation period. The median follow-up period was 16 years (range 5-45 years). In total over 64% of the patients were affected by at least 1 chronic health condition, including endocrine disruptions in 19.1% of the patients. Moreover, secondary neoplasms occurred in 9.1% of the study participants. Conclusion: German childhood cancer survivors are affected by multiple therapy-related sequelae. A comprehensive network of late effects clinics should be established to ensure specialized and risk-adapted care for every childhood cancer survivor in Germany.

Journal Title
Oncology Research and Treatment
Volume
41
Issue
7-8
Citation
Oncology Research and Treatment 41.7/8 (2018): S. 430-436. <https://www.karger.com/Article/FullText/488203> © 2018 S. Karger GmbH, Freiburg
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