Time Trends in Incidence of Pathological and Etiological Stroke Subtypes during 16 Years: The Erlangen Stroke Project

dc.contributor.authorKolominsky-Rabas, Peter L.
dc.contributor.authorWiedmann, Silke
dc.contributor.authorWeingärtner, Michael
dc.contributor.authorLiman, Thomas G.
dc.contributor.authorEndres, Matthias
dc.contributor.authorSchwab, Stefan
dc.contributor.authorBuchfelder, Michael
dc.contributor.authorHeuschmann, Peter U.
dc.date.accessioned2016-04-28
dc.date.available2016-04-27
dc.date.created2015
dc.date.issued2016-04-28
dc.description.abstractBackground: Population-based data, which continuously monitors time trends in stroke epidemiology are limited. We investigated the incidence of pathological and etiological stroke subtypes over a 16 year time period. Methods: Data were collected within the Erlangen Stroke Project (ESPro), a prospective, population-based stroke register in Germany covering a total study population of 105,164 inhabitants (2010). Etiology of ischemic stroke was classified according to the Trial of Org 10172 in Acute Stroke Treatment (TOAST) criteria. Results: Between January 1995 and December 2010, 3,243 patients with first-ever stroke were documented. The median age was 75 and 55% were females. The total stroke incidence decreased over the 16 year study period in men (Incidence Rate Ratio 1995-1996 vs. 2009-2010 (IRR) 0.78; 95% CI 0.58-0.90) but not in women. Among stroke subtypes, a decrease in ischemic stroke incidence (IRR 0.73; 95% CI 0.57-0.93) and of large artery atherosclerotic stroke (IRR 0.27; 95% CI 0.12-0.59) was found in men and an increase of stroke due to small artery occlusion in women (IRR 2.33; 95% CI 1.39-3.90). Conclusions: Variations in time trends of pathological and etiological stroke subtypes were found between men and women that might be linked to gender differences in the development of major vascular risk factors in the study population.en
dc.format.extent24-29
dc.identifier.citationNeuroepidemiology 2015; 44: 24-29. <https://www.karger.com/Article/FullText/371353> © 2015 S. Karger AG, Basel
dc.identifier.doihttps://doi.org/10.1159/000371353
dc.identifier.opus-id7112
dc.identifier.urihttps://open.fau.de/handle/openfau/7112
dc.identifier.urnurn:nbn:de:bvb:29-opus4-71125
dc.language.isoen
dc.rights.urihttp://www.gesetze-im-internet.de/urhg/index.html
dc.subjectStroke
dc.subjectEpidemiology
dc.subjectIncidence
dc.subjectTime trends
dc.subjectRegister
dc.subject.ddcDDC Classification::6 Technik, Medizin, angewandte Wissenschaften :: 61 Medizin und Gesundheit :: 610 Medizin und Gesundheit
dc.titleTime Trends in Incidence of Pathological and Etiological Stroke Subtypes during 16 Years: The Erlangen Stroke Projecten
dc.typearticle
dcterms.publisherFriedrich-Alexander-Universität Erlangen-Nürnberg (FAU)
local.journal.issue1
local.journal.titleNeuroepidemiology
local.journal.volume44
local.sendToDnbfree*
local.subject.fakultaetMedizinische Fakultät
local.subject.sammlungUniversität Erlangen-Nürnberg / Allianzlizenzen: Alle Beiträge sind mit Zustimmung der Rechteinhaber aufgrund einer DFG-geförderten Allianzlizenz frei zugänglich. / Allianzlizenzen 2015
Files
Original bundle
Now showing 1 - 1 of 1
Loading...
Thumbnail Image
Name:
7112_kolomsky_time.pdf
Size:
151.32 KB
Format:
Adobe Portable Document Format
Description: